How to take vitamin e dosage. Vitamin E: how to take and in what dosage? Immune system, skin and mucous membranes
A diet high in selenium and sulfur-containing amino acids reduces the need for vitamin E.
Primary isolated deficiency of vitamin E in humans is rare. Deficiency can be caused by defects in absorption, metabolism, or increased consumption of the vitamin under oxidative stress. Deficiency occurs as a result of insufficient intake of the vitamin from food, therefore a balanced diet does not cause vitamin E deficiency. Secondary deficiency in the human body can occur as a result of the following reasons: after gastric resection, with celiac disease, enterocolitis, chronic pancreatitis, cystic fibrosis, cholestasis, short bowel syndrome , A-beta-lipoproteinemia, after prolonged parenteral nutrition.
Vitamin E deficiency is manifested by severe free radical-induced cell and tissue disorders, especially in preterm infants, such as respiratory distress syndrome, retrolental fibroplasia, and hemolytic anemia. With a clear deficiency of vitamin E, neuromuscular disorders are observed, in particular, spinocerebellar degeneration.
Oral forms of vitamin E are not suitable for the treatment of vitamin E deficiency conditions associated with impaired intestinal absorption. Intestinal absorption disorders can be observed, for example, in cholestasis, A-beta-lipoproteinemia and in premature babies. In these cases, parenteral administration of the vitamin is required.
Vitamin E should be used with caution if there is an increased risk of thromboembolism.
High doses of vitamin E may increase the effect of anticoagulants. In patients receiving anticoagulants, the state of hemostasis should be carefully monitored.
Pregnancy and lactation
It is well known that there is no clear relationship between maternal and fetal blood concentrations of vitamin E. Short-term vitamin E supplementation by pregnant women before childbirth significantly increases vitamin E status only in the mother. It is believed that vitamin E does not effectively cross the placenta into the baby's bloodstream. The mechanisms of regulation of placental transmission remain not fully understood; a regulatory role of α-TTP in the transfer of α-tocopherol across the placental barrier is assumed.
Animal studies with vitamin E showed no evidence of teratogenic effects.
Vitamin E can be used in an amount corresponding to the daily requirement. Controlled studies of the use of vitamin E capsules at a dose of 100 IU in animals and in pregnant women have not been conducted. Although no serious side effects are known to date, the drug should be used with caution during pregnancy.
During breastfeeding, the use of the drug is recommended only if the potential benefit outweighs the risk to the child.
Interactions
Vitamin E increases the effectiveness of anticonvulsants in patients with epilepsy who have an increased content of lipid peroxidation products in the blood. Anticonvulsants such as phenobarbital, phenytoin, and carbamazepine may decrease plasma vitamin E concentrations.
Enhances the effect of steroid and non-steroidal anti-inflammatory drugs, antioxidants. Increases the effectiveness and reduces the toxicity of cardiac glycosides, as well as vitamins A and D. The appointment of vitamin E in high doses can cause a deficiency of vitamin A in the body.
The simultaneous use of vitamin E at a dose of more than 400 IU / day with anticoagulants (coumarin and indandione derivatives), antiplatelet agents (clopidogrel and dipyridamole), non-steroidal anti-inflammatory drugs (aspirin, ibuprofen, etc.) increases the risk of hypoprothrombinemia and bleeding.
Cholestyramine, colestipol, isoniazid, orlistat, sucralfate and fat substitute olestra, mineral oils reduce the absorption of alpha-tocopheryl acetate.
High doses of iron increase oxidative processes in the body, which increases the need for vitamin E.
With the simultaneous use of alpha-tocopheryl acetate with cyclosporine, the absorption of the latter increases.
Very high doses of vitamin E have been shown in animal experiments to limit the absorption of vitamins A and K.
Oral iron supplements may decrease the absorption of vitamin E in the intestines when both drugs are taken at the same time. In this case, it is desirable that these drugs be taken at intervals of about 4 hours.
In conditions of malabsorption, combined deficiency of vitamin D and vitamin K, as well as in the case of the use of vitamin K antagonists (for example, oral anticoagulants), coagulation should be carefully monitored, since a sharp decrease in vitamin K in the body is possible.
Patients receiving anticoagulant therapy or patients with vitamin K deficiency should not use vitamin E without careful medical supervision due to an increased risk of bleeding.
Vitamin E is often called the vitamin of beauty, health and fertility. So it is, because it is this element that regulates the work of the genital organs in women. What is this substance, why you need to take vitamins and how to take vitamin E for women, let's find out the answers to all questions.
Vitamin E for women. General information
Vitamin E or the main substance "tocopherol" is produced in different forms. The pharmaceutical industry has long learned to produce this substance not only in the form of capsules, but also in the form of a liquid, as well as in tablets. Tocopherol is found in many vitamin complexes and dietary supplements, but most often women buy the liquid form.
The main thing you need to pay attention to right away is that vitamin E, produced in vials and capsules, is a synthetic form, because real vitamin E (“tocopherols” of plant origin) can only be obtained by squeezing wheat germ. This method is very expensive, so it is almost impossible to see a natural vitamin in a pharmacy. But the combined form (synthetics and a natural product) is currently being produced by some pharmaceutical companies.
Vitamin E. Benefits and harms for women
In order to understand the full significance of this substance, let's get acquainted with the properties of vitamin E.
First of all, tocopherol is a very, very powerful antioxidant that helps to remove everything unnecessary from the human body: and these are toxins, carcinogens. If you take vitamins correctly every day (including vitamin E), then you can prolong youth and prevent the development of many terrible diseases.
In addition, it will help:
- strengthen blood vessels (prevention of cardiovascular diseases, blood clots);
- improve the functioning of the circulatory system, as well as improve the supply of nutrients;
- saturate the body with oxygen;
- as already mentioned, removes harmful substances. As well as chemical and radionuclides, which is very important for people living in contaminated areas;
- will also help stop the aging process of the body;
- protect a person from the attack of bacteria and viruses;
- help to cope with physical stress and increase efficiency;
- lowers pressure;
- reduce oxidation processes;
- in complex treatment lowers blood sugar;
- will help the speedy healing of soft tissues (wounds, scars);
- smoothes the skin, prevents the appearance of age spots;
- strengthens the immune system;
- has a positive effect on the acceleration of metabolic processes in the body, and also regulates the level of hormones (reproduction of the reproductive system);
- promotes better absorption of vitamin A.
As you can see, this vitamin has many benefits. It is especially important to take this substance to women of reproductive age.
Vitamin E benefits for women:
- Vitamin of youth and beauty - this is how you can briefly characterize the properties of this substance. It is a powerful antioxidant that protects the cells of the body from premature aging, helps to restore oxidation processes, which means that in this way the formation of cancer cells is protected. If vitamin E is not enough, then the cells are very sensitive to toxins, and this in turn leads to a weakening of the immune system.
- Vitamin E is simply necessary for the normal functioning of the whole organism, as it helps to saturate each of our cells with oxygen. And this, in turn, is the prevention of blood clots and the development of atherosclerosis. Alas, vitamin E cannot completely cure this disease.
- Vitamin E plays a very important role for a woman of childbearing age - his doctors in the antenatal clinic sometimes call it “vitamin for reproduction”. If a man has a deficiency of this substance, then the production of active spermatozoa decreases. If there is not enough vitamin in women, then this leads to a violation of the cycle of menstruation, as well as a decrease in sexual desire.
- Partially compensates for the lack of estrogen (female hormone), will help improve the condition of the mucous membranes, get rid of depression and other unpleasant symptoms during menopause.
- Regular consumption of tocopherol improves appearance skin, it becomes smoother and more elastic, unpleasant sensations caused by lack of moisture disappear.
- Vitamin E is part of the products for hair, body and nails. Hair becomes silky, stops falling out, nails become stronger. But in order to achieve the effect, it is necessary not only to apply vitamin E locally, but also to take tocopherol orally.
Vitamin E deficiency in women can lead to:
- apathy;
- weaknesses;
- the appearance of pigmentation;
- the skin becomes flabby;
- muscle weakness, dystrophy;
- miscarriage.
On the dangers of this substance for the female body, we can say that a small overdose does not cause any negative consequences.
But, if the daily norm of tocopherol is doubled, then a person may experience symptoms such as:
- nausea;
- vomit;
- bowel disorder;
- increase in pressure;
- allergic reactions.
If you stop taking a vitamin, but these Negative consequences pass by themselves.
Important: in the first couple of months from the moment of conception, the future mother should in no case exceed the indicated dosage, because the fetus has a risk of developing a pathology of the cardiovascular system.
It is undesirable to take this vitamin with such drugs:
- anticoagulants;
- iron-containing preparations;
- enhances the action of non-steroidal and steroid drugs: "Aspirin", "Ibuprofen" and "Diclofenac");
- with thromboembolism, as well as myocardial infarction and cardiosclerosis, it should be taken with extreme caution. Only on the recommendation of the attending physician and under constant supervision.
Vitamin E for women when planning a pregnancy
Pregnant women and women who are planning a pregnancy should take a particularly responsible approach to taking vitamin E.
The point is that in recent times more women are admitted to the hospital for preservation early dates. The body is unable to cope with the increased load, oxidative processes increase. To prevent this from happening, vitamin E should be taken at the planning stage or in the first weeks of pregnancy.
It has the following benefits for the female body:
- increases the possibility of conception;
- reduce the risk of placental discharge;
- reduces fatigue;
- regenerates uterine cells;
- improve the functioning of the genital organs (relieve dryness of the mucous membranes);
- normalizes the level of hormones;
- protects a woman from miscarriage.
With improper use of tocopherol, it is possible:
- lack of oxygen in the fetus;
- the contraction of the walls of the uterus increases, which leads to miscarriage;
- the fetus increases the risk of developing pathologies of the vascular and cardiac systems;
- there is a high risk of having a baby prematurely.
The norm of vitamin E per day for women
In order to know the individual norm of tocopherol, it is necessary to donate blood for analysis and consult with a specialist. The fact is that vitamin E is fat-soluble and it gradually accumulates in adipose tissue. If there is a lot of vitamin, then a person may feel weakness, nausea and other unpleasant symptoms.
How much vitamin E does a woman need per day? Normally, the daily dose for women is 8 mg, for men this figure increases by 2 mg, that is, the norm is 10 mg, and for children, no more than 5 mg can be taken per day. Pregnant women and mothers who are breastfeeding should take 10 to 15 mg of vitamin E per day, as directed by a doctor.
How to take vitamin E capsules for women
The rule for taking this drug is the same for everyone: you need to take vitamin E in the morning, preferably immediately after the first meal. In no case should you drink capsules on an empty stomach and half an hour or an hour before meals.
Important: before taking the capsule, you need to eat something fatty. Together with other drugs, and even more so with antibiotics, you can not drink vitamin E capsules.
The capsule is not chewed in the mouth, but immediately swallowed with a glass of water. Immediately after taking tocopherol, you can drink a glass of orange juice, eat a tangerine, a few slices of grapefruit, drink a glass of rosehip broth.
When and to whom you can increase the daily allowance:
- Increase the daily dose is allowed for people who have reached the age of 50;
- In diseases of the liver (chronic stage), gall and pancreas.
- After injuries, operations and severe burns.
- During childbearing and breastfeeding.
- After the stress.
- At the same time, taking contraceptive or hormonal drugs (the interval between taking a vitamin and medication is 1 hour).
- Athletes and people with heavy physical exertion.
- With a deficiency of selenium in the body.
What foods contain vitamin E
These foods contain natural vitamin E:
- vegetable fats: sunflower, olive, soybean, corn, sesame, pumpkin, sea buckthorn, cedar, wheat oils;
- butter;
- nuts: a lot of tocopherol in peanuts and almonds;
- fruits and seeds: avocado, mango, cereals, bran, corn;
- products: liver, in fish (salmon), lettuce, broccoli, spinach, green onions, carrots, milk and hard cheese;
- also, some plants contain a lot of tocopherol: these are raspberry, nettle and dandelion leaves, sea buckthorn fruits, rose hips.
Attention: In search of the answer "Why is vitamin E useful for a woman", try not to overdo it, because all of the above products are very high in calories and you can quickly gain extra pounds. To prevent this from happening, you need to eat more zinc-containing foods, as well as foods high in ascorbic acid, selenium and vitamin C.
Vitamin E for hair
Beautiful and silky flowing hair is the dream of every woman. Proper care and masks with vitamin E will help improve the condition of the curls, make them beautiful, get rid of dandruff, dryness and breaking ends.
Effective beauty recipes:
- buy an ampoule solution of vitamin E at the pharmacy. When washing, you need to add half a teaspoon of the product to the shampoo, lather on your hair. But before rinsing off, linger for 60 seconds. Wash off the shampoo as usual;
- in the same way, you can add a little tocopherol to a balm or hair mask right before applying it to the curls;
- onion mask: onion juice (1-2 onions, depending on size), mixed with 1 tsp. vitamin, applied to clean, damp hair. Holding time - no more than 5 minutes;
- how to avoid split ends: burdock oil is mixed in the amount of 3 tbsp. with vitamin E - 1 tsp, the mixture must be heated in a water bath, rubbed into the roots, wrapped in a towel and left for 60 minutes;
- from falling out: pharmacy chamomile and dry nettle leaves - 3 tablespoons each, dry black bread - 2 slices, a teaspoon of vitamin E. Herbs are brewed, infused, the broth is filtered, the active substance is added. In a small amount of herbal decoction, you need to knead stale bread, mix everything together and apply the gruel to the hair roots. Keep 20 minutes;
- for nutrition: burdock oil - a tablespoon, tocopherol - a teaspoon and the yolk of one egg. All components need to be mixed, slightly heated, rubbed into the roots. This mask is washed off with warm water after an hour;
- vitamin cocktail for hair: half a teaspoon of liquid vitamin E and A, yolk chicken egg, linseed oil - 2 tablespoons, vitamin B-3 in ampoules - 5 drops, eleutherococcus extract - a tablespoon. Mix all the ingredients, rub it thoroughly into the scalp, leave for half an hour.
Vitamin E for women's skin
Any skin needs care, so do not neglect cleansers, moisturizing, nourishing masks. In combination and with the right approach, you can delay the appearance of wrinkles and prolong youth.
Making masks at home
- whitening cottage cheese mask: whipped cottage cheese (2 tablespoons) with olive oil (unrefined), an ampoule of vitamin E is added. The mask is applied to the face for 15 minutes;
- anti-aging: low-fat homemade yogurt (1 tbsp), 1 tsp. honey (if thickened, then you need to melt), lemon juice - 1 tsp, vitamin E - 5 drops. Stir, apply to cleansed skin, keep for 15 minutes.
Rules for everyone:
- Before using, you need to check the reaction of the body to avoid swelling, redness and discomfort. Apply a little mask or cream on your hand, wait 30 minutes. If everything is in order, then you can apply on the face.
- The face must be cleaned with lotion, remove the remnants of dirt with cleansing milk or foam.
- Steam your face over a steam bath with the addition of herbs.
- Use a scrub to thoroughly cleanse open pores.
- Apply a thick layer of homemade mask on the skin. The mask is not applied to sensitive and thin skin around the eyes.
- The average exposure time of the mask is from 10 to 40 minutes. Try to lie down during this time.
- Wash off the mask with a warm decoction of herbs or just warm water.
- After washing, you can apply a cream on the skin.
You will see for yourself when you see the result - it will not be difficult to make such a mask for yourself, especially since all the components can be found in every home. Now you know why women need vitamin E. Be healthy and beautiful!
Tocopherol acetate (tocopherol)
Composition and form of release of the drug
10 pieces. - cellular contour packings (3) - packs of cardboard.
10 pieces. - cellular contour packings (6) - packs of cardboard.
pharmachologic effect
Vitamin E. It has an antioxidant effect, participates in the biosynthesis of heme and proteins, cell proliferation, tissue respiration, and other important processes of tissue metabolism, prevents hemolysis of erythrocytes, and prevents increased permeability and capillary fragility.
Pharmacokinetics
When taken orally, absorption is 50%; in the process of absorption, it forms a complex with lipoproteins (intracellular carriers of tocopherol). Bile acids are required for absorption. It binds to alpha 1 and beta lipoproteins, partially to serum. If protein metabolism is disturbed, transport is hindered. Cmax is reached after 4 hours. It is deposited in the adrenal glands, pituitary gland, testes, adipose and muscle tissue, erythrocytes, and liver. More than 90% is excreted in the bile, 6% - by the kidneys.
Indications
Hypovitaminosis, conditions of convalescence after diseases occurring with a febrile syndrome, high physical activity, old age, diseases of the ligamentous apparatus and muscles. Climacteric vegetative disorders. with overwork, asthenic neurasthenic syndrome, primary muscular dystrophy, post-traumatic, post-infectious secondary myopathy. Degenerative and proliferative changes in the joints and ligaments of the spine and large joints.
Contraindications
Hypersensitivity to tocopherol.
Dosage
Usually prescribed 100-300 mg / day. If necessary, the dose can be increased to 1 g / day.
Side effects
Maybe: allergic reactions; when taken in high doses - epigastric pain; with i / m administration - soreness, infiltration at the injection site.
Vitamin E (tocopherol) is a natural fat-soluble antioxidant that protects our cells from destruction. Taking this vitamin is one of the ways to maintain youth and restore reproductive abilities. Vitamin E is available in capsules, dragees and tablets for oral administration in various dosages. In our country, it is produced by many pharmaceutical enterprises, there are also imported drugs. A large selection of dietary supplements with tocopherols on the website of the Iherb online store.
Release form and composition
The drug is produced in the form of dosage forms for oral administration - capsules and dragees. An oil solution of 50 ml in a bottle is also produced (about 30 drops in 1 ml). The composition of the drug includes the active active substance and auxiliary agents.
The active substance is tocopherol. Natural tocopherols are a mixture of eight isomers: alpha, beta, gamma and delta tocopherols and the same isomers of tocotrienols. The most common are alpha-tocopherols. The inscription on the bottle with a natural substance looks like this: d-alpha-tocopherol. Particle d speaks about the natural origin of tocopherol.
Synthetic drug (tocopherol acetate) is made on the basis of alpha-tocopherol. The inscription on the bottle looks like this: dl-alpha-tocopherol. The particle dl speaks about the synthetic nature of the vitamin.
The amount of the active substance in one dose is expressed in milligrams (mg) or in international units - IU:
- 100 mg is 110 IU of a synthetic or 150 IU of a natural compound;
- 1 IU of a natural substance is equal to 0.67 mg, 1 IU of a synthetic one is 1 mg.
Pharmacological properties
The pharmacological properties of vitamin E include the mechanism of its action (pharmacodynamics) and the mechanism of penetration of this substance into the body, its absorption, promotion and excretion (pharmacokinetics).
Pharmacodynamics (mechanism of action)
A few decades ago, vitamin E was perceived only as an antioxidant. It was known that it inhibits the activity of free radicals - toxic aggressive molecules formed in the process of metabolism and destroying cell membranes. This leads to premature aging of the body and disruption of a number of functions.
A number of other equally important functions of this compound are currently known:
- It activates the formation of hemoglobin and myoglobin (retains and deposits oxygen in the muscles), catalase and peroxidase (enzymes that promote the decomposition of hydrogen peroxide into water and oxygen). There is stimulation of tissue respiration, activation of metabolism and removal of toxic metabolic products, rejuvenation of the body.
- Improves the absorption of vitamin A, promotes skin rejuvenation. After a course of taking a vitamin, a person looks younger.
- Suppresses the synthesis of cholesterol. Therefore, the connection is especially useful for people suffering from ischemic disease hearts.
- Inhibits hemolysis (destruction) of red blood cells.
- Improves the condition of capillaries.
- In men, it prevents the development of impotence and infertility.
- Restores the menstrual cycle and reproductive function of women; during pregnancy inhibits the permeability of the placenta for toxic substances.
- Taking vitamin E is a way to slow the progression of Alzheimer's disease.
- Has an anti-cancer effect.
Pharmacokinetics
The absorption of the compound in the intestine is facilitated by bile and fats. In order for this fat-soluble vitamin to be properly absorbed in the intestines, it is taken after meals, and fats must be present in the food. But even in this case, half of the dose taken is absorbed.
When absorbed, vitamin E binds to fat-protein compounds that act as a vehicle. Tocopherols are deposited in hormonal, adipose tissue, as well as in other organs and tissues. They can accumulate, causing hypervitaminosis. This compound is excreted in various ways: mainly with bile and feces, and a little through the kidneys.
Indications for taking vitamin E
Tocopherols are needed by adults and children. Indications for the use of this vitamin are very diverse.
For adults
Indications for adults are:
- hypovitaminosis E;
- a state of weakness (asthenia) after acute infections that occurred with a high temperature;
- heavy physical exertion during work or sports; helps in quick recovery after exercise;
- overwork, accompanied by nervous disorders: irritable weakness, insomnia, etc.;
- elderly age; needed to suppress the aging process:
- diseases accompanied by weakness of the muscular-ligamentous apparatus;
- muscular dystrophy (reduction of muscles in volume) after a long stay in a stationary state with injuries and serious illnesses;
- menopause with severe disorders of the vegetative nervous system- hot flashes to the upper half of the body, palpitations, etc .; an indication is also osteoprosis, which develops with a decrease hormonal background: preparations with vitamin E stimulate the secretion of gonadotropic hormones of the pituitary gland, which, in turn, stimulates the production of sex hormones;
- degenerative-dystrophic diseases of the musculoskeletal system - osteoarthritis and osteochondrosis; helps strengthen the muscles that support the skeleton;
- chronic skin diseases (psoriasis, etc.);
- menstrual disorders, infertility in women; risk of miscarriage;
- impotence and infertility in men.
For kids
It has a positive effect on the development and restoration of health in children. Indications for appointment are:
- lagging behind the child in height and weight;
- violation of neuropsychic and emotional development;
- prevention of respiratory diseases in newborns, especially premature ones;
- restoration of health after infections, serious illnesses and operations.
During pregnancy and lactation
During pregnancy, vitamin E, produced in capsules, is needed by the woman's body, but in certain dosages selected by the doctor. During pregnancy, both its deficiency and excess are dangerous. Hypervitaminosis E can lead to premature maturation of the placenta and premature birth.
While breastfeeding, before taking the drug, you should consult your doctor to clarify the dosage and duration of the course of administration.
Side effects and allergies
In the dosages prescribed by the doctor, tocopherol is well tolerated. Side effects possible after taking large doses and manifest as abdominal pain, diarrhea, nausea. Allergic reactions are also possible in the form of a variety of itchy rashes and angioedema (Quincke's edema) with respiratory failure. If you suspect an allergy, you should immediately stop taking the capsules.
Contraindications and warnings
Despite good tolerance, the drugs have contraindications:
- individual intolerance and allergy.
Take, with caution, correctly, starting with small doses, you need:
- with increased blood clotting;
- myocardial infarction;
- severe heart disease with impaired function of this organ;
- stable high blood pressure;
- elevated levels of triglycerides in the blood.
Reception and dosage
It will be correct to consult with your doctor how much and how to take vitamin E in capsules or dragees. But sometimes this is not possible, so it is worth knowing the average dosages recommended for adults and children.
For adults
Vitamin E capsules are taken orally. You need to drink it after or during meals. The average daily dose for an adult is 100-200 IU. The course of treatment is 4 - 8 weeks. If necessary, the course can be repeated after three months. For persons with constant heavy physical exertion, the average daily dose can be increased to 600 and above, but not more than 1100 IU of synthetic or 1500 IU of natural.
For kids
- infants 5 - 10 IU;
- preschoolers 20 - 40 IU;
- schoolchildren 50 - 100 IU.
The dosage of vitamin E in capsules is at least 100 IU, therefore, if the daily dose for children is less than 100 IU, it is recommended to drink the drug in the dosage form in the form of an oily solution in drops. 1 ml of oil solution contains about 30 drops. The duration of the course of treatment and dosage is determined by the doctor.
UNIT CONVERTER: VITAMIN E
Natural Natural in the form of acetate Natural in the form of tocopherolic acid succinate Synthetic Synthetic in the form of acetate Synthetic in the form of tocopherolic acid succinate
Substance form
IU mg mcg g
Since vitamin E can accumulate in the body, an overdose is possible only with a long course of treatment in large daily doses:
- if you use from 400 to 800 IU per day for more than 8 weeks, you start to get sick and dizzy, there is a breakdown, nausea, diarrhea, abdominal pain, blurred vision;
- if you use more than 800 IU per day for more than 8 weeks, these symptoms increase, there is a risk of developing thromboembolism (the formation of blood clots in the vessels with their further detachment and blockage of significant vessels), thrombophlebitis (inflammation of the walls of blood vessels blocked by a thrombus), impaired liver, kidney function and cardiovascular system, blindness due to retinal hemorrhage.
If you suspect an overdose, you should immediately stop taking tocopherol and consult a doctor.
drug interaction
Instructions for use of vitamin E capsules contain information on its interaction with other drugs. Tocopherol intake:
- Potentiates (enhances) the action of:
- glucocorticoid hormones (prednisolone);
- non-steroidal anti-inflammatory drugs (ibuprofen, diclofenac);
- cardiac glycosides (digoxin, strophanthin).
- Reduces toxicity:
- cardiac glycosides;
- fat-soluble vitamins A and D.
Tocopherols should not be used together with iron. If there is a need to drink such drugs, it is correct to take a break of at least two hours between taking tocopherol and iron.
special instructions
The instructions for use noted that vitamin E promotes tissue repair, so it is often prescribed for chronic relapsing diseases accompanied by exhaustion and loss of strength. Dosages and duration of administration are determined by the attending physician.
Terms and conditions of storage
Capsules and tablets can be stored at a temperature of 10 - 25 ° C, avoiding direct sunlight.
The drug retains its medicinal properties during two years. The countdown is from the date of manufacture.
The preparation of vitamin E is prescribed orally after meals, in doses selected by the doctor. The capsule should be swallowed without chewing and washed down with the required amount of water.
The dosage of vitamin E in capsules is:
- for antioxidant treatment- 200-400 mg 1-2 times a day;
- for prevention and treatment embryonic pathologies of the fetus-100-200 mg 1 time per day;
- for miscarriage prevention- 100 mg 1-2 times a day, 10-14 days;
- at menstrual disorders- 300-400 mg per day, starting from the 16th day of the cycle, conduct 5-6 courses;
- with inflammatory diseases of the musculoskeletal system- 100 mg 1-2 times a day, course 1-2 months;
- endocrine disorders- 300-500 mg per day;
- at eye and skin diseases- 100-200 mg 1-2 times a day together with vitamin A;
- at impotence- 100-300 mg per day, the course is 30 days.
pharmachologic effect
pharmachologic effect
- Acetate, which is part of the alpha-tocopherol preparation, exhibits antioxidant properties;
- Accelerates metabolism in tissues;
- Protects vessels and blood cells from damage;
- Supports the function of the sex glands;
- Slows down degenerative processes in the cardiovascular system;
- Protects cell membranes from the damaging effects of free radicals;
- Accelerates the formation of protein and slows down the exchange of cholesterol.
Pharmacodynamics and pharmacokinetics
Absorbed from the intestine in the presence of bile acids, bioavailability - about 50%. It is transported by blood with the help of specific transport proteins.
Peak plasma levels are reached 4 hours after ingestion. Disruptions in protein metabolism impair the transport of tocopherol acetate.
Accumulates in the liver, adrenal glands, sex and endocrine glands, adipose tissue. Metabolized in the liver, excreted in the bile and urine.
What is vitamin E capsules good for?
genitourinary system
- responsible for the health of the reproductive system;
- increases the likelihood of conception and normal development of the fetus;
- alleviates the condition of breast cancer and premenstrual syndrome;
- increases libido.
Musculoskeletal and cardiovascular system
- prevents thrombosis and stabilizes the walls of blood vessels;
- makes muscles strong and enduring, prevents cramps;
- facilitates the course of infectious and inflammatory diseases joints.
Immune system, skin and mucous membranes
- relieves symptoms of diabetes;
- stimulates the immune system;
- accelerates the regeneration of skin injuries;
- slows down skin aging, makes it supple and smooth.
What is vitamin E capsules for?
Vitamin E capsules are prescribed in such cases:
- infertility;
- vitamin E deficiency;
- developmental disorders of the musculoskeletal system;
- inflammation of the ligaments and joints;
- menstrual disorder;
- risk of miscarriage;
- low sperm motility;
- increased physical activity;
- inflammatory and infectious diseases skin;
- recovery after illnesses and surgical interventions;
- as an antioxidant in inflammatory diseases;
- in old age to slow down aging.
Contraindications
Taking vitamin E capsules is contraindicated in such cases:
- individual sensitivity to the components of the drug;
- cardiosclerosis;
- acute condition with myocardial infarction;
- hyperfunction of the thyroid gland;
- an overdose of vitamin E;
- use with caution in children under 12 years of age.
Vitamin E capsules
Vitamin E preparations
Vitamin E Vitrum - the price in the pharmacy and the composition of the capsule
Transparent soft capsules, 60 pieces in a glass bottle or 12 pieces in a contour pack.
One capsule contains 400 mg of alpha-tocopherol acetate in terms of pure substance.
Additional components- gelatin, glycerin, purified water.
Price — 35 / 117 UAH / 95 / 340 rubles.
Aevit - the price in the pharmacy and the composition of the capsule
Soft yellow capsules with a seam, 10, 20 or 50 capsules per package.
One capsule contains 100 mg of vitamin E and 100,000 IU of vitamin A.
Additional components- sunflower oil, gelatin, glycerin, additive E 218, E 216.
Price — 15 UAH / 44 rubles.
Acevit - the price in the pharmacy and the composition of the capsule
Red soft gelatin capsules, 30 pieces per pack.
One capsule contains tocopherol acetate 22.8 mg, beta carotene 5.1 mg, ascorbic acid 70 mg.
Additional components- red palm oil, aerosil, gelatin.
Price — 210 UAH / 580 rubles.
Vitamin E capsules - reviews
Most reviews of vitamin E capsules are positive. Depending on the indications, the drug had a pharmacological effect indicated in the instructions. Side effects rarely manifested, mainly in the form of skin allergic reactions.